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西湖大学生医中心2023年4月科研支撑成果

作者:浏览量:时间:2024-07-08

1. Zhang, X. F., F. H. Yang, X. C. Zhan, T. Bian, Z. H. Xing, Y. C. Lu, and Y. G. Shi. "Structural Basis of Pre-Trna Intron Removal by Human Trna Splicing Endonuclease." [In English]. Article.Molecular Cell83, no. 8 (Apr 2023): 1328-+.

北京时间2023年4月6日,西湖大学生命科学学院施一公团队在《分子细胞》(Molecular Cell) 在线发表了题为“Structural basis of pre-tRNA intron removal by human tRNA splicing endonuclease”的最新研究论文,报道了pre-tRNA结合人源tRNA剪接内切酶 (tRNA splicing endonuclease, TSEN) 复合物处于“预催化”和“催化后”两种状态的高分辨率结构,结合体外生化,揭示了TSEN复合物识别和剪切pre-tRNA内含子的分子机理。


原文链接:https://www.cell.com/molecular-cell/fulltext/S1097-2765(23)00205-8


2.Cao T, Bai Y, Buschbeck P, et al. An unexpected hydratase synthesizes the green light-absorbing pigment fucoxanthin[J]. The Plant Cell, 2023, 35(8): 3053-3072.

北京时间2023年4月27日,西湖大学生命科学学院李小波团队在The Plant Cell在线发表了题为An unexpected hydratase synthesizes the green light-absorbing pigment fucoxanthin的最新研究论文,报道了"海洋杂色藻岩藻黄素(Fucoxanthin)生物合成途径中末端酶,其催化了岩藻黄素中特征的酮基(keto)的产生"

原文链接:unexpected hydratase synthesizes the green light-absorbing pigment fucoxanthin | The Plant Cell | Oxford Academic (oup.com)


3.Chi, X. Y., L. Y. Xia, G. Y. Zhang, X. M. Chi, B. D. Huang, Y. Y. Zhang, Z. S. Chen, et al."Comprehensive Structural Analysis Reveals Broad-Spectrum Neutralizing Antibodies against Sars-Cov-2 Omicron Variants." [In English]. Article.Cell Discovery9, no. 1 (Apr 2023): 23 37.

原文链接:https://doi.org/10.1038/s41421-023-00535-1.


4.Li, Y. N., Y. P. Shen, Z. W. Hu, and R. H. Yan. "Structural Basis for the Assembly of the DNA Polymerase Holoenzyme from a Monkeypox Virus Variant." [In English]. Article.Science Advances9, no. 16 (Apr 2023): 11 eadg2331.

原文链接:https://doi.org/10.1126/sciadv.adg2331.


5.Wang, C. C., Z. Y. Guo, C. Chu, Y. C. Lu, X. F. Zhang, and X. C. Zhan. "Two Assembly Modes for Sin3 Histone Deacetylase Complexes." [In English]. Article.Cell Discovery9, no. 1 (Apr 2023): 11 42.

原文链接:https://doi.org/10.1038/s41421-023-00539-x.


6.Wang C, Guo Z, Chu C, et al. Two assembly modes for SIN3 histone deacetylase complexes[J]. Cell Discovery, 2023, 9(1): 42.

原文链接:Two assembly modes for SIN3 histone deacetylase complexes | Cell Discovery (nature.com)


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