Ø实验室简介

面向化学、材料、环境、食品等领域，以小分子、聚合物为研究对象，依靠色质谱技术进行定性定量分析及化合物纯化制备，开展小分子，尤其是异构体分子的色质谱方法研究。

Ø仪器与服务

测试表征：色谱分离定性定量、聚合物分子量范围测定、色谱方法建立与筛选、一级质谱（高/低分辨）、二级质谱（高分辨）、淌度分析、化合物（含异构体）拆分、化合物（含异构体）纯化、元素含量分析测定、单细胞元素分析、蛋白质纯化。服务种类：定性分析，定量分析；化合物纯化

Ø人员介绍

陈银娟：2016年毕业于复旦大学化学系，2016-2018年在同济大学进行博士后研究。博士及博后期间基于氢氘交换质谱法以及飞行时间质谱、离子淌度谱、三重四极杆液质联用仪、飞行时间-红外光解离光谱技术对小分子非共价复合物、自组装化合物、团簇离子结构进行研究。在飞行时间质谱仪、离子淌度仪、氢氘交换质谱仪、常压离子源等方面具有良好的研究背景，在Talanta, Phys. Chem. Chem. Phys、Analytical Methods等杂志上发表一作SCI论文6篇，申请中国发明专利4项，其中1项授权专利。

ØIntroduction

This lab focuses on qualitative analysis, quantitative analysis and compound purification of small molecules and polymers in chemistry-, material-, environment- and food-related areas via chromatography and mass spectrometry techniques. We are dedicated to the development of chromatographic and/or mass spectrometric method, especially for isomer analysis.

ØInstrument and Services

Instruments

①Gas Chromatography (GC)(Agilent,GC-7890B, equipped with FID&TCD)

②Ultra-high Performance Liquid Chromatography (UPLC)(Waters, H-Class)

③Gas Chromatography-Mass Spectrometry (GC-MS)(ThermoFisher, ISQ 7000, equipped with MS&FID)

④Ultra-high Performance Liquid Chromatography-QuadropoleMass Spectrometry (UPLC-MS)(Waters, H-Class/SQD2; equipped with MS &PDA)

⑤Ultra-high Performance Convergence Chromatography (UPCC)(Waters)

⑥Advanced Polymer Chromatography (APC)(Waters)

⑦Gel Permeation Chromatography (GPC)(Waters)

⑧Preparative Liquid Chromatography(Waters, prep-150)

⑨Protein Purification System(GE, AKTA-Pure)

⑩Preparative Supercritical Fluid Chromatography (SFC)(Waters, Prep-100)

⑪Inductively-Coupled Plasma Mass Spectrometry (ICP-MS)(ThermoFisher,iCAPRQ)

⑫Ultra-high Performance Liquid Chromatography-Time-of-Flight Mass Spectrometry (UPLC-IMS-TOF)(Waters, Synapt-G2-Si)

Services

qualitative analysis by LC/LC-MS/GC/GC-MS;quatitativeanalysis by LC/LC-MS/GC/GC-MS; MS analysis; tandem mass analysis/MS2; chromatographic method creation via UPLC/ UPCC; mass range determination of polymer, ISM analysis, compound/isomer purification, element determination, single cell analysis by ICP-MS, protein purification

ØMembers

Dr. Yinjuan CHEN received herPh.Ddegree from department of chemistry at Fudan University at 2016, then she completed thePostdocresearch at Tongji University during 2016 to 2019. She specializes in compound analysis via HDX MS, time-of-flight mass spectrometry, ion mobility spectroscopy, liquid chromatography-mass spectrometry. The relative research articles are publish inTalanta, Phys. Chem. Chem. Phys, Analytical Methods, etc.